RNU6-498P

Across TCGA pan-cancer cohorts, RNU6-498P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-498P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-498P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-498P expression acts as an unfavorable survival marker.

SKCM, LAML, and ESCA are the cancer types where RNU6-498P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.048	0.738	<.001	117	view →
LAML	DFS	Tertile	All	0.202	0.581	.006	36	view →
ESCA	DFS	Tertile	All	0.075	0.533	<.001	36	view →
PRAD	DFS	Tertile	All	0.600	0.936	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNU6-498P–SKCM (DFS)

Open the SKCM breakdown →