RNU6-494P

Across TCGA patient cohorts, RNU6-494P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,244 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-494P-associated GO terms across cancer lineages are Regulation of chromatin organization, Protein localization to microtubule organizing center, and Obsolete DNA methylation. Each is linked with RNU6-494P in more than 12 cancer types. Because this analysis shows association rather than direction, both RNU6-494P-to-partner and partner-to-RNU6-494P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by RNU6-494P-low versus RNU6-494P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-494P→partner) and Y-score (partner→RNU6-494P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of chromatin organization →	+0.056	+0.753	<.001	<.001	3	13
ESCA	Protein localization to microtubule organizing center →	+0.070	+0.938	<.001	<.001	3	12
STAD	Obsolete DNA methylation →	+0.039	+0.554	<.001	<.001	3	12
ESCA	Heterochromatin organization →	+0.054	+0.752	<.001	<.001	3	12
LIHC	Regulation of nucleotide-excision repair →	+0.039	+0.049	.002	.005	2	12
LIHC	DNA integrity checkpoint signaling →	+0.039	+0.043	.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,244 associations by consensus.

Regulation of chromatin organization by RNU6-494P expression — ESCA

Explore this box plot interactively →