RNU6-476P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-476P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-476P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-476P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-476P expression acts as an unfavorable survival marker, although some lineages such as READ and LUAD show a favorable association.

THCA, READ, and UVM are the cancer types where RNU6-476P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCADFSTertileII,III,IV0.7430.976.00161view →
READOSMedianII,III,IV1.0000.778<.00141view →
UVMOSTertileIII,IV0.3820.801<.00141view →
KICHDFSQuartileIII,IV0.2851.000.01539view →
LUADDFSTertileII,III,IV0.6470.351.00239view →
COADDFSQuartileAll0.4280.724.00330view →
ACCOSMedianIV0.3220.676.01327view →
KIRPDFSTertileIII,IV0.2060.672.00424view →
CHOLOSMedianIV0.2080.948.01021view →
PRADOSMedianAll0.9751.000.00818view →
LUSCDFSTertileIII,IV0.2370.880.00416view →
BRCADFSTertileIII,IV0.8470.712.01712view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration