RNU6-218P

Across TCGA patient cohorts, RNU6-218P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,684 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-218P-associated GO terms across cancer lineages are Mitotic DNA integrity checkpoint signaling, Cell cycle G2/M phase transition, and DNA replication. Each is linked with RNU6-218P in more than 19 cancer types. Because this analysis shows association rather than direction, both RNU6-218P-to-partner and partner-to-RNU6-218P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA integrity checkpoint signaling grouped by RNU6-218P-low versus RNU6-218P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-218P→partner) and Y-score (partner→RNU6-218P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitotic DNA integrity checkpoint signaling →	+0.068	+0.677	<.001	<.001	3	20
ESCA	Cell cycle G2/M phase transition →	+0.070	+0.599	<.001	<.001	3	20
ESCA	DNA replication →	+0.078	+0.715	<.001	<.001	3	20
ESCA	Recombinational repair →	+0.070	+0.806	<.001	<.001	3	20
ESCA	DNA integrity checkpoint signaling →	+0.072	+0.800	<.001	<.001	3	20
THYM	Regulation of DNA-directed DNA polymerase activity →	+0.052	+0.400	<.001	<.001	2	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,684 associations by consensus.

Mitotic DNA integrity checkpoint signaling by RNU6-218P expression — ESCA

Explore this box plot interactively →