RNU6-218P

Across TCGA pan-cancer cohorts, RNU6-218P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU6-218P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-218P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-218P expression acts as an unfavorable survival marker, although some lineages such as LAML and STAD show a favorable association.

KIRC, ACC, and UVM are the cancer types where RNU6-218P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.490	0.690	<.001	142	view →
ACC	OS	Tertile	III,IV	0.308	0.661	.006	76	view →
UVM	OS	Tertile	All	0.037	0.835	<.001	54	view →
PCPG	DFS	Tertile	All	0.719	0.928	<.001	42	view →
LIHC	DFS	Quartile	All	0.245	0.481	.001	38	view →
MESO	DFS	Tertile	II,III,IV	0.132	0.537	.010	27	view →
LAML	DFS	Quartile	All	0.558	0.360	.023	22	view →
CESC	OS	Quartile	III,IV	0.164	0.582	.007	20	view →
KIRP	DFS	Tertile	II,III,IV	0.385	0.736	.021	18	view →
THCA	OS	Tertile	IV	0.790	1.000	.016	12	view →
DLBC	OS	Median	All	0.718	1.000	.045	11	view →
KICH	DFS	Quartile	II,III,IV	0.287	0.748	.038	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNU6-218P–KIRC (DFS)

Open the KIRC breakdown →