RNU6-2

Across TCGA patient cohorts, RNU6-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,394 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RNU6-2-associated GO terms across cancer lineages are Spliceosomal tri-snRNP complex assembly, DNA replication initiation, and Female meiosis chromosome segregation. Each is linked with RNU6-2 in more than 10 cancer types. Because this analysis shows association rather than direction, both RNU6-2-to-partner and partner-to-RNU6-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal tri-snRNP complex assembly grouped by RNU6-2-low versus RNU6-2-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-2→partner) and Y-score (partner→RNU6-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Spliceosomal tri-snRNP complex assembly →	-0.072	-1.430	<.001	<.001	3	11
GBM	DNA replication initiation →	+0.063	+0.620	<.001	.001	3	10
GBM	Female meiosis chromosome segregation →	+0.097	+0.691	<.001	<.001	3	9
THYM	Meiotic sister chromatid cohesion →	+0.062	+0.783	<.001	<.001	3	9
ACC	Outer mitochondrial membrane organization →	+0.042	+0.852	<.001	<.001	2	10
ESCA	DNA unwinding involved in DNA replication →	+0.062	+0.481	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,394 associations by consensus.

Spliceosomal tri-snRNP complex assembly by RNU6-2 expression — UCS

Explore this box plot interactively →