RNU6-1291P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1291P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-1291P data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RNU6-1291P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1291P expression acts as an unfavorable survival marker, although some lineages such as CESC and ESCA show a favorable association.

OV, BLCA, and DLBC are the cancer types where RNU6-1291P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVOSTertileII,III,IV0.4080.692.03154view →
BLCAOSTertileIV0.0820.575.01136view →
DLBCDFSTertileII,III,IV0.0220.837<.00136view →
LUADOSTertileAll0.2560.697.02418view →
KIRPOSTertileII,III,IV0.1990.771.03012view →
TGCTDFSTertileAll0.1680.688.0116view →
CESCDFSTertileII,III,IV1.0000.758.0356view →
ESCADFSTertileAll1.0000.603.0423view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU6-1291P–OV (OS)

Kaplan–Meier survival curve for RNU6-1291P RNA-high vs -low samples in OV.

Open the OV breakdown →

Exploration