RNU6-1291P

Across TCGA pan-cancer cohorts, RNU6-1291P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU6-1291P’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RNU6-1291P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1291P is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

UCEC and LUSC are the cancer types where RNU6-1291P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1291P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.403	.002	2	view →
LUSC	All	All	+0.087	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNU6-1291P–UCEC

Open the UCEC breakdown →