RNU6-1257P

Across TCGA patient cohorts, RNU6-1257P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,508 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNU6-1257P-associated GO terms across cancer lineages are Lysosomal transport, Regulation of RNA splicing, and Regulation of Ras protein signal transduction. Each is linked with RNU6-1257P in more than 23 cancer types. Because this analysis shows association rather than direction, both RNU6-1257P-to-partner and partner-to-RNU6-1257P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosomal transport grouped by RNU6-1257P-low versus RNU6-1257P-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-1257P→partner) and Y-score (partner→RNU6-1257P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Lysosomal transport →	+0.061	+0.201	<.001	<.001	3	24
UCEC	Regulation of RNA splicing →	+0.055	+0.170	<.001	<.001	3	23
ESCA	Regulation of Ras protein signal transduction →	+0.042	+0.377	<.001	<.001	3	23
UCEC	Regulation of mRNA splicing, via spliceosome →	+0.062	+0.099	<.001	<.001	3	23
THYM	Regulation of small GTPase mediated signal transduction →	+0.042	+0.155	<.001	<.001	3	23
THYM	Obsolete selective autophagy →	+0.062	+0.177	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,508 associations by consensus.

Lysosomal transport by RNU6-1257P expression — THYM

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