RNU6-1257P

Across TCGA pan-cancer cohorts, RNU6-1257P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-1257P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNU6-1257P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1257P expression acts as an unfavorable survival marker, although some lineages such as LIHC and KIRC show a favorable association.

CESC, LUSC, and UCS are the cancer types where RNU6-1257P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	IV	0.219	0.557	.022	54	view →
LUSC	DFS	Tertile	III,IV	0.405	0.918	.010	44	view →
UCS	DFS	Tertile	All	0.155	0.537	.004	36	view →
LIHC	OS	Tertile	II,III,IV	0.917	0.567	.009	27	view →
KIRP	OS	Tertile	IV	0.111	0.503	<.001	18	view →
KIRC	DFS	Tertile	III,IV	0.800	0.553	.019	12	view →
READ	DFS	Tertile	III,IV	0.222	0.765	.001	12	view →
COAD	OS	Tertile	IV	0.140	0.657	.035	9	view →
ACC	DFS	Tertile	All	0.394	0.681	.030	9	view →
THCA	OS	Tertile	IV	0.832	1.000	.035	9	view →
ESCA	OS	Median	All	0.449	1.000	.011	8	view →
BRCA	DFS	Tertile	III,IV	0.866	0.768	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RNU6-1257P–CESC (DFS)

Open the CESC breakdown →