RNU6-1257P

Across TCGA pan-cancer cohorts, RNU6-1257P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6-1257P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNU6-1257P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-1257P is over-expressed in tumor.

COAD, KIRP, and LUAD are the cancer types where RNU6-1257P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1257P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.162	.010	4	view →
KIRP	Female	II,III,IV	+0.337	.047	2	view →
LUAD	Male	All	+0.447	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU6-1257P–COAD

Open the COAD breakdown →