RNU6-122P

Across TCGA patient cohorts, RNU6-122P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,601 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-122P-associated GO terms across cancer lineages are Regulation of RNA splicing, Positive regulation of telomere maintenance, and Telomere maintenance. Each is linked with RNU6-122P in more than 21 cancer types. Because this analysis shows association rather than direction, both RNU6-122P-to-partner and partner-to-RNU6-122P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by RNU6-122P-low versus RNU6-122P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-122P→partner) and Y-score (partner→RNU6-122P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of RNA splicing →	+0.068	+0.897	<.001	<.001	3	22
STAD	Positive regulation of telomere maintenance →	+0.057	+0.709	<.001	<.001	3	20
STAD	Telomere maintenance →	+0.052	+0.767	<.001	<.001	3	20
STAD	Positive regulation of DNA-templated transcription, elongation →	+0.052	+0.626	<.001	<.001	3	19
DLBC	Epigenetic regulation of gene expression →	+0.057	+0.444	.002	<.001	2	20
ESCA	Organelle disassembly →	+0.053	+0.812	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,601 associations by consensus.

Regulation of RNA splicing by RNU6-122P expression — ESCA

Explore this box plot interactively →