RNU6-122P

Across TCGA pan-cancer cohorts, RNU6-122P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-122P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-122P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-122P expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

KICH, BLCA, and UCEC are the cancer types where RNU6-122P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.043	0.971	<.001	48	view →
BLCA	DFS	Tertile	IV	0.931	0.248	<.001	48	view →
UCEC	OS	Tertile	IV	0.254	0.607	.007	36	view →
KIRP	OS	Tertile	III,IV	0.454	0.799	.007	33	view →
LGG	DFS	Tertile	All	0.196	0.475	.001	33	view →
KIRC	DFS	Quartile	All	0.408	0.675	.015	24	view →
DLBC	OS	Tertile	III,IV	0.172	1.000	.014	18	view →
OV	OS	Quartile	II,III,IV	0.754	0.671	.012	12	view →
READ	DFS	Tertile	All	0.250	0.625	.029	8	view →
STAD	OS	Tertile	IV	0.918	0.399	.049	6	view →
ESCA	DFS	Median	III,IV	0.430	0.248	.025	6	view →
HNSC	OS	Tertile	III,IV	0.747	0.333	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-122P–KICH (DFS)

Open the KICH breakdown →