RNU6-1177P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1177P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU6-1177P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RNU6-1177P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1177P expression acts as an unfavorable survival marker, although some lineages such as BLCA and HNSC show a favorable association.

LIHC, ESCA, and COAD are the cancer types where RNU6-1177P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSTertileAll0.1270.715<.00178view →
ESCAOSTertileAll0.3940.643.00146view →
COADOSTertileIV0.2120.673.00336view →
KICHOSTertileII,III,IV0.1550.880<.00136view →
LUSCOSTertileAll0.3210.428.00933view →
SKCMDFSTertileAll0.2980.616.00730view →
THYMOSTertileAll0.3520.884<.00124view →
BLCAOSTertileIII,IV0.6470.332.02621view →
CHOLOSTertileII,III,IV0.0240.601.02518view →
MESOOSTertileIV0.0770.592.01918view →
UCECDFSTertileIII,IV0.6660.812.00518view →
LGGOSTertileAll0.6070.889.01415view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

Exploration