Across TCGA pan-cancer cohorts, RNU6-1177P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-1177P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU6-1177P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-1177P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUSC, BRCA, and THCA are the cancer types where RNU6-1177P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1177P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	III,IV	+0.393	.014	4	view →
BRCA	Female	All	+0.308	.003	4	view →
THCA	Male	II,III,IV	−0.432	.022	3	view →
STAD	All	All	+0.501	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-1177P RNA expression & survival · all RNU6-1177P data types