Across TCGA pan-cancer cohorts, RNU6-1176P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-1176P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU6-1176P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1176P is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

LUSC, BRCA, and UCEC are the cancer types where RNU6-1176P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1176P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.243	<.001	5	view →
BRCA	All	III,IV	−0.625	<.001	2	view →
UCEC	All	All	−0.306	.027	2	view →
KIRC	All	II,III,IV	+0.133	.029	2	view →
LIHC	Female	All	−0.120	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-1176P RNA expression & survival · all RNU6-1176P data types