RNU6-1176P

associated omics data
RNA, U6 small nuclear 1176, pseudogeneGenealiases: []

Q-omics provides the consensus-scored RNU6-1176P profile across patient tissues and cancer cell-line models. RNU6-1176P expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, RNU6-1176P is differentially expressed in 5, with the highest sampling consensus in LUSC. Additionally, RNU6-1176P RNA expression shows 12,711 significant protein co-abundance associations, with the highest sampling consensus in LUAD. Together, these results highlight COAD, LUSC, and LUAD as cancer lineages where RNU6-1176P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes RNU6-1176P survival associations across molecular data types. RNU6-1176P RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
RNU6-1176P data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier17LIHC (39)view →
This table ranks reproducible RNU6-1176P RNA expression–survival associations across cancer types. High RNU6-1176P expression shows unfavorable associations in COAD, LIHC, UCEC, KIRP and PAAD, but favorable associations in LAML. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify COAD as the clearest survival context for RNU6-1176P RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSTertileIII,IV0.2640.715.00139view →
LIHCDFSTertileII,III,IV0.1210.359.00739view →
UCECOSTertileAll0.7560.883.00136view →
KIRPDFSTertileIV0.0880.502<.00136view →
LAMLDFSMedianAll0.4750.286.00430view →
PAADOSTertileAll0.4140.638.00330view →
Pink = unfavorable, green = favorable. all 17 lineages →

RNU6-1176P-COAD (OS)

Kaplan–Meier survival curve for RNU6-1176P RNA expression in COAD: high vs low expression groups.

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Tumor vs Normal expression

This table summarizes RNU6-1176P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in LUSC for RNA.
RNU6-1176P data typeExpression analysisLineage consensusLineage of highest sampling consensus
RNABox plot5LUSC (5)view →
This table ranks reproducible tumor–normal expression differences for RNU6-1176P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-1176P shows lower tumor expression in LUSC, BRCA, UCEC and LIHC and higher tumor expression in KIRC. The LUSC box plot shows higher RNU6-1176P RNA expression in normal versus tumor tissue (log2 FC = −0.243, t-test p < 0.001).
LineageGenderStageFold-changepSampling consensus
LUSCAllAll−0.243<.0015view →
BRCAAllIII,IV−0.625<.0012view →
UCECAllAll−0.306.0272view →
KIRCAllII,III,IV+0.133.0292view →
LIHCFemaleAll−0.120.0312view →
Green = repressed in tumor. all 5 lineages →

RNU6-1176P-LUSC

Tumor-vs-normal expression box plot for RNU6-1176P in LUSC.

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Cross-omics associations

This table shows molecular features associated with RNU6-1176P in patient tissues and cancer cell lines. In patient samples, RNU6-1176P shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
Protein (mass-spec)12,711LUAD (4713)view →
RNA10,580ESCA (3400)view →