RNU6-1121P

Across TCGA patient cohorts, RNU6-1121P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,771 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible RNU6-1121P-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA poly(A) tail shortening, Regulation of DNA repair, and snRNA metabolic process. Each is linked with RNU6-1121P in more than 24 cancer types. Because this analysis shows association rather than direction, both RNU6-1121P-to-partner and partner-to-RNU6-1121P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA poly(A) tail shortening grouped by RNU6-1121P-low versus RNU6-1121P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-1121P→partner) and Y-score (partner→RNU6-1121P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.044	+0.284	<.001	<.001	3	25
ESCA	Regulation of DNA repair →	+0.058	+0.450	<.001	<.001	3	25
ESCA	snRNA metabolic process →	+0.045	+0.312	<.001	<.001	3	25
DLBC	Stress granule assembly →	+0.069	+0.268	.006	<.001	3	25
ESCA	Microtubule anchoring →	+0.055	+0.415	<.001	<.001	3	25
STAD	Cytokinesis →	+0.041	+0.262	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,771 associations by consensus.

Regulation of nuclear-transcribed mRNA poly(A) tail shortening by RNU6-1121P expression — ESCA

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