RNU6-1121P

Across TCGA pan-cancer cohorts, RNU6-1121P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RNU6-1121P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-1121P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1121P expression acts as an unfavorable survival marker, although some lineages such as ESCA and READ show a favorable association.

KICH, UCEC, and UVM are the cancer types where RNU6-1121P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	All	0.644	0.960	<.001	97	view →
UCEC	DFS	Tertile	All	0.766	0.848	.027	90	view →
UVM	OS	Tertile	All	0.739	0.957	.007	81	view →
TGCT	OS	Tertile	III,IV	0.003	1.000	<.001	54	view →
ESCA	OS	Median	II,III,IV	0.667	0.360	.003	48	view →
READ	OS	Tertile	II,III,IV	1.000	0.540	.008	24	view →
DLBC	DFS	Tertile	All	0.400	0.669	.029	18	view →
LGG	DFS	Median	All	0.802	0.699	.007	13	view →
LUAD	DFS	Tertile	IV	0.262	0.663	.039	12	view →
PRAD	OS	Quartile	All	0.968	0.995	.012	12	view →
OV	OS	Tertile	IV	0.266	0.413	.042	12	view →
SKCM	DFS	Tertile	IV	0.040	0.620	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

RNU6-1121P–KICH (DFS)

Open the KICH breakdown →