RNU6-100P

Across TCGA patient cohorts, RNU6-100P RNA expression is significantly associated with the go_rna of many other GO terms, with 7,100 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible RNU6-100P-associated GO terms across cancer lineages are Nuclear-transcribed mRNA poly(A) tail shortening, Ribosome-associated ubiquitin-dependent protein catabolic process, and Obsolete histone methylation. Each is linked with RNU6-100P in more than 31 cancer types. Because this analysis shows association rather than direction, both RNU6-100P-to-partner and partner-to-RNU6-100P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA poly(A) tail shortening grouped by RNU6-100P-low versus RNU6-100P-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-100P→partner) and Y-score (partner→RNU6-100P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.091	+1.201	<.001	<.001	3	32
CHOL	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.100	+1.210	<.001	<.001	3	31
DLBC	Obsolete histone methylation →	+0.086	+1.273	<.001	<.001	3	31
STAD	Hormone-mediated signaling pathway →	+0.041	+0.545	<.001	<.001	3	31
DLBC	Negative regulation of gene expression, epigenetic →	+0.089	+1.236	<.001	<.001	3	31
DLBC	Positive regulation of DNA-templated transcription initiation →	+0.088	+1.299	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,100 associations by consensus.

Nuclear-transcribed mRNA poly(A) tail shortening by RNU6-100P expression — DLBC

Explore this box plot interactively →