RNU6-100P

Across TCGA pan-cancer cohorts, RNU6-100P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU6-100P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-100P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-100P expression acts as an unfavorable survival marker, although some lineages such as BRCA and READ show a favorable association.

UCEC, UVM, and HNSC are the cancer types where RNU6-100P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.456	0.745	<.001	106	view →
UVM	DFS	Tertile	III,IV	0.231	0.670	<.001	54	view →
HNSC	OS	Quartile	II,III,IV	0.403	0.667	.002	54	view →
LIHC	DFS	Tertile	All	0.420	0.600	.001	44	view →
LUSC	DFS	Tertile	II,III,IV	0.241	0.674	.003	37	view →
OV	OS	Quartile	IV	0.531	0.902	.004	36	view →
COAD	DFS	Quartile	II,III,IV	0.540	0.695	.003	35	view →
DLBC	DFS	Tertile	All	0.563	0.951	.003	30	view →
LUAD	DFS	Median	IV	0.306	0.764	.010	18	view →
BRCA	OS	Median	III,IV	0.946	0.858	.006	14	view →
CHOL	DFS	Median	IV	0.082	0.753	.008	12	view →
SARC	OS	Median	All	0.672	0.786	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNU6-100P–UCEC (DFS)

Open the UCEC breakdown →