RNU5F-2P

Across TCGA patient cohorts, RNU5F-2P RNA expression is significantly associated with the go_rna of many other GO terms, with 4,947 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU5F-2P-associated GO terms across cancer lineages are Regulation of microtubule-based process, tRNA metabolic process, and Positive regulation of protein ubiquitination. Each is linked with RNU5F-2P in more than 7 cancer types. Because this analysis shows association rather than direction, both RNU5F-2P-to-partner and partner-to-RNU5F-2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule-based process grouped by RNU5F-2P-low versus RNU5F-2P-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU5F-2P→partner) and Y-score (partner→RNU5F-2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Regulation of microtubule-based process →	+0.102	+0.038	<.001	.003	3	7
LUSC	tRNA metabolic process →	+0.130	+0.038	<.001	.003	2	8
LUSC	Positive regulation of protein ubiquitination →	+0.126	+0.060	<.001	.004	2	7
LUSC	Mitochondrial gene expression →	+0.150	+0.038	<.001	.003	3	6
LUSC	Macromolecule methylation →	+0.125	+0.059	<.001	.004	3	6
LUSC	Mitotic DNA integrity checkpoint signaling →	+0.150	+0.068	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,947 associations by consensus.

Regulation of microtubule-based process by RNU5F-2P expression — LUSC

Explore this box plot interactively →