RNU5F-2P

Across TCGA pan-cancer cohorts, RNU5F-2P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU5F-2P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU5F-2P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU5F-2P expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

UCS, LIHC, and STAD are the cancer types where RNU5F-2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	All	0.068	0.524	<.001	144	view →
LIHC	OS	Tertile	All	0.108	0.786	<.001	81	view →
STAD	DFS	Tertile	IV	0.097	0.506	<.001	36	view →
LUSC	OS	Tertile	III,IV	0.147	0.664	.028	36	view →
KIRC	DFS	Tertile	IV	0.192	0.623	<.001	24	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
BLCA	OS	Tertile	II,III,IV	0.825	0.693	.031	12	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU5F-2P–UCS (DFS)

Open the UCS breakdown →