Across TCGA patient cohorts, RNU5E-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,120 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU5E-1-associated GO terms across cancer lineages are Mitochondrial genome maintenance, Spliceosomal tri-snRNP complex assembly, and Positive regulation of mitotic cell cycle phase transition. Each is linked with RNU5E-1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNU5E-1-to-partner and partner-to-RNU5E-1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU5E-1→partner) and Y-score (partner→RNU5E-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitochondrial genome maintenance →	+0.036	+0.567	<.001	<.001	3	12
DLBC	Spliceosomal tri-snRNP complex assembly →	-0.068	-0.911	<.001	.002	1	14
ESCA	Positive regulation of mitotic cell cycle phase transition →	+0.046	+0.742	.005	<.001	3	11
ESCA	Regulation of organelle assembly →	+0.033	+0.641	.005	<.001	2	12
ESCA	Regulation of RNA binding →	+0.033	+0.615	<.001	<.001	3	11
SARC	DNA integrity checkpoint signaling →	+0.025	+0.635	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,120 associations by consensus.

Exploration

RNU5E-1 survival (RNA) · tumor vs normal (RNA) · all RNU5E-1 data types