Across TCGA patient cohorts, RNU4-53P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,692 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU4-53P-associated GO terms across cancer lineages are Macromolecule methylation, Positive regulation of DNA repair, and Negative regulation of mRNA metabolic process. Each is linked with RNU4-53P in more than 20 cancer types. Because this analysis shows association rather than direction, both RNU4-53P-to-partner and partner-to-RNU4-53P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU4-53P→partner) and Y-score (partner→RNU4-53P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Macromolecule methylation →	+0.045	+0.214	<.001	<.001	3	21
STAD	Positive regulation of DNA repair →	+0.034	+0.446	<.001	<.001	3	21
ESCA	Negative regulation of mRNA metabolic process →	+0.053	+0.587	.002	<.001	3	20
UVM	Positive regulation of double-strand break repair →	+0.037	+0.192	<.001	.001	3	20
UVM	Protein acetylation →	+0.052	+0.338	<.001	<.001	3	20
STAD	Mitochondrial transport →	+0.036	+0.429	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,692 associations by consensus.

Exploration

RNU4-53P survival (RNA) · tumor vs normal (RNA) · all RNU4-53P data types