Across TCGA patient cohorts, RNU4-21P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,810 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU4-21P-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Protein acylation, and Nucleotide-excision repair. Each is linked with RNU4-21P in more than 22 cancer types. Because this analysis shows association rather than direction, both RNU4-21P-to-partner and partner-to-RNU4-21P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU4-21P→partner) and Y-score (partner→RNU4-21P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of stem cell population maintenance →	+0.077	+0.587	<.001	<.001	3	23
STAD	Protein acylation →	+0.058	+0.688	<.001	<.001	3	23
STAD	Nucleotide-excision repair →	+0.051	+0.625	<.001	<.001	3	23
STAD	Telomere maintenance →	+0.061	+0.765	<.001	<.001	3	23
ESCA	Regulation of signal transduction by p53 class mediator →	+0.073	+0.543	<.001	<.001	3	22
STAD	Regulation of post-translational protein modification →	+0.063	+0.764	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,810 associations by consensus.

Exploration

RNU4-21P survival (RNA) · tumor vs normal (RNA) · all RNU4-21P data types