Q-omics provides the consensus-scored RNU2-54P profile across patient tissues and cancer cell-line models. RNU2-54P expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, RNU2-54P RNA expression shows 5,443 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight HNSC, and COAD as cancer lineages where RNU2-54P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU2-54P survival associations across molecular data types. RNU2-54P RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU2-54P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	HNSC (72)	view →

This table ranks reproducible RNU2-54P RNA expression–survival associations across cancer types. High RNU2-54P expression shows unfavorable associations in HNSC, KIRP, SKCM, STAD and BRCA. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for RNU2-54P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.082	0.711	<.001	72	view →
KIRP	OS	Tertile	All	0.180	0.904	<.001	45	view →
SKCM	DFS	Tertile	III,IV	0.043	0.597	<.001	42	view →
STAD	OS	Tertile	IV	0.075	0.496	.013	30	view →
BRCA	OS	Tertile	All	0.174	0.580	.009	30	view →

Pink = unfavorable, green = favorable. all 5 lineages →

RNU2-54P-HNSC (OS)

Kaplan–Meier survival curve for RNU2-54P RNA expression in HNSC: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with RNU2-54P in patient tissues and cancer cell lines. In patient samples, RNU2-54P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	5,443	COAD (2540)	view →
Protein (mass-spec)	4,700	HNSC (2688)	view →