RNU11-4P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU11-4P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU11-4P data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNU11-4P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU11-4P expression acts as an unfavorable survival marker, although some lineages such as TGCT show a favorable association.

READ, ACC, and SKCM are the cancer types where RNU11-4P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READOSTertileAll0.6380.934<.00187view →
ACCOSTertileAll0.1330.686.00454view →
SKCMDFSTertileIV0.0400.501<.00154view →
CHOLOSTertileII,III,IV0.2530.796.01845view →
KIRCOSTertileAll0.5660.687.00941view →
THCADFSTertileII,III,IV0.7950.944.00127view →
PAADDFSTertileIII,IV0.1180.734.01418view →
KIRPOSTertileIV0.1110.503<.00118view →
SARCDFSTertileAll0.1650.518.02118view →
GBMOSTertileAll0.0890.415.0219view →
MESOOSTertileIV0.3710.634.0269view →
COADOSTertileIII,IV0.4870.804.0109view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration