RNU11-2P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU11-2P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU11-2P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU11-2P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU11-2P expression acts as an unfavorable survival marker, although some lineages such as BLCA and LAML show a favorable association.

BLCA, LUSC, and UVM are the cancer types where RNU11-2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSTertileAll1.0000.534.004105view →
LUSCOSTertileIV0.0010.673.01439view →
UVMOSTertileAll0.2180.696.01436view →
LIHCOSTertileIII,IV0.0790.737.00436view →
LAMLDFSQuartileAll0.7030.447.01130view →
LGGOSTertileAll0.7300.401.00121view →
SKCMDFSTertileII,III,IV0.4040.728.00318view →
LUADDFSTertileIV0.3330.671.04818view →
READDFSTertileII,III,IV0.2060.723.00618view →
OVOSQuartileIII,IV0.7520.860.00118view →
CESCDFSTertileAll0.8030.496.03612view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU11-2P–BLCA (OS)

Kaplan–Meier survival curve for RNU11-2P RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration