RNU1-88P

Across TCGA pan-cancer cohorts, RNU1-88P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU1-88P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU1-88P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU1-88P expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

BRCA, ACC, and LIHC are the cancer types where RNU1-88P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	II,III,IV	0.833	0.901	.006	51	view →
ACC	DFS	Tertile	II,III,IV	0.178	0.566	.009	48	view →
LIHC	OS	Tertile	All	0.519	0.712	.001	45	view →
HNSC	DFS	Tertile	IV	0.503	0.281	.007	39	view →
KIRC	OS	Tertile	II,III,IV	0.357	0.568	.002	38	view →
SKCM	OS	Tertile	III,IV	0.831	0.670	.020	21	view →
UVM	DFS	Tertile	All	0.257	0.637	.034	18	view →
UCEC	OS	Tertile	All	0.641	0.683	.020	18	view →
GBM	DFS	Quartile	All	0.190	0.327	.010	15	view →
READ	OS	Tertile	All	1.000	0.597	.032	12	view →
PRAD	OS	Tertile	All	0.972	0.998	.003	12	view →
KIRP	OS	Tertile	All	0.553	0.715	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU1-88P–BRCA (DFS)

Open the BRCA breakdown →