RNU1-88P

Across TCGA pan-cancer cohorts, RNU1-88P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU1-88P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU1-88P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU1-88P is over-expressed in tumor.

BRCA, UCEC, and LUSC are the cancer types where RNU1-88P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-88P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.332	.025	4	view →
UCEC	All	IV	+0.880	.024	2	view →
LUSC	All	All	+0.124	.015	2	view →
CHOL	All	All	+0.418	.036	1	view →
LUAD	Female	II,III,IV	+0.200	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RNU1-88P–BRCA

Open the BRCA breakdown →