RNU1-61P

Across TCGA patient cohorts, RNU1-61P mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU1-61P-associated genes across cancer lineages are RNU1-77P, MIR1224, and RNA5SP408. Each is linked with RNU1-61P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU1-61P-to-partner and partner-to-RNU1-61P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-77P grouped by RNU1-61P-low versus RNU1-61P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU1-61P→partner) and Y-score (partner→RNU1-61P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-77P →	+0.520	+5.081	.009	.008	3	1
UCEC	MIR1224 →	+0.816	+5.081	<.001	.008	3	1
UCEC	RNA5SP408 →	+0.927	+5.186	<.001	.007	3	1
UCEC	RN7SKP12 →	+0.576	+5.551	<.001	.004	3	1
UCEC	PRAMEF13 →	+0.117	+6.453	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

RNU1-77P by RNU1-61P expression — UCEC

Explore this box plot interactively →