RNU1-61P

Across TCGA pan-cancer cohorts, RNU1-61P RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RNU1-61P data layer compared with 1 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU1-61P RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNU1-61P expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

SKCM, UVM, and STAD are the cancer types where RNU1-61P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.431	0.283	<.001	52	view →
UVM	DFS	Tertile	II,III,IV	0.201	0.641	.005	51	view →
STAD	DFS	Median	IV	0.157	0.566	.003	27	view →
LUAD	DFS	Median	All	0.457	0.266	.011	25	view →
CESC	OS	Median	All	0.850	0.748	.024	20	view →
READ	DFS	Tertile	III,IV	0.418	0.781	.007	15	view →
HNSC	DFS	Quartile	III,IV	0.792	0.639	.006	12	view →
MESO	DFS	Median	All	0.263	0.587	.020	9	view →
LGG	OS	Quartile	All	0.745	0.834	.014	9	view →
LUSC	DFS	Quartile	All	0.547	0.676	.021	9	view →
LIHC	DFS	Tertile	III,IV	0.632	0.256	.025	9	view →
CHOL	OS	Median	II,III,IV	0.737	0.333	.016	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RNU1-61P–SKCM (OS)

Open the SKCM breakdown →