RNU1-61P

Across TCGA pan-cancer cohorts, RNU1-61P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RNU1-61P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU1-61P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU1-61P is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

LUSC, COAD, and LUAD are the cancer types where RNU1-61P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU1-61P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−1.415	<.001	8	view →
COAD	Female	All	−0.315	.002	8	view →
LUAD	Male	All	−0.994	<.001	7	view →
KIRC	All	All	+0.358	.005	6	view →
BRCA	All	III,IV	−0.507	.002	2	view →
KICH	All	II,III,IV	−0.471	.032	2	view →
UCEC	All	All	−0.462	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RNU1-61P–LUSC

Open the LUSC breakdown →