RNF41

Across TCGA cell cohorts, RNF41 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,315 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNF41-associated GO terms across cancer lineages are Negative regulation of transcription by RNA polymerase III, Regulation of nucleotide-excision repair, and tRNA transport. Each is linked with RNF41 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNF41-to-partner and partner-to-RNF41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription by RNA polymerase III grouped by RNF41-low versus RNF41-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF41→partner) and Y-score (partner→RNF41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of transcription by RNA polymerase III →	+0.174	+0.643	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of nucleotide-excision repair →	+0.113	+0.780	<.001	.006	3	13
PANCREAS	tRNA transport →	+0.135	+0.818	<.001	<.001	3	12
SKIN	Lipoprotein localization →	+0.123	+0.619	<.001	<.001	3	12
STOMACH	Regulation of smoothened signaling pathway →	+0.057	+0.617	.001	<.001	3	12
LUNG_NSCLC_LUSC	Organelle transport along microtubule →	+0.084	+0.765	.002	.005	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,315 associations by consensus.

Negative regulation of transcription by RNA polymerase III by RNF41 expression — STOMACH

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