RNF40

Across TCGA patient cohorts, RNF40 protein abundance is significantly associated with the RNA expression of many other genes, with 13,864 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNF40-associated genes across cancer lineages are KIF14, HELLS, and KIF11. Each is linked with RNF40 in more than 7 cancer types. Because this analysis shows association rather than direction, both RNF40-to-partner and partner-to-RNF40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF40 versus KIF14 in LUAD, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF40→partner) and Y-score (partner→RNF40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KIF14 →	+0.999	+0.113	<.001	<.001	3	8
HNSC	HELLS →	+0.809	+0.160	<.001	<.001	3	8
HNSC	KIF11 →	+0.868	+0.186	<.001	<.001	3	8
HNSC	KNTC1 →	+0.836	+0.194	<.001	<.001	3	8
HNSC	ASPM →	+1.029	+0.188	<.001	<.001	3	8
HNSC	SMC3 →	+0.758	+0.182	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,864 associations by consensus.

RNF40 vs KIF14 — LUAD

Explore this scatter interactively →