RNF40

Across TCGA cell cohorts, RNF40 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,405 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNF40-associated GO terms across cancer lineages are Regulation of chromatin organization, RNA export from nucleus, and Regulation of nucleotide-excision repair. Each is linked with RNF40 in more than 15 cancer types. Because this analysis shows association rather than direction, both RNF40-to-partner and partner-to-RNF40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by RNF40-low versus RNF40-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF40→partner) and Y-score (partner→RNF40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of chromatin organization →	+0.123	+0.565	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.106	+0.784	<.001	<.001	3	15
KIDNEY	Regulation of nucleotide-excision repair →	+0.111	+0.974	<.001	<.001	3	15
URINARY_TRACT	CAMP/PKA signal transduction →	+0.213	+0.704	<.001	<.001	3	14
LUNG_SCLC	Spliceosomal tri-snRNP complex assembly →	+0.107	+0.563	<.001	.003	3	14
BONE	Transcription elongation-coupled chromatin remodeling →	+0.130	+0.642	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,405 associations by consensus.

Regulation of chromatin organization by RNF40 expression — BONE

Explore this box plot interactively →