RNF214

Across TCGA patient cohorts, RNF214 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,126 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNF214-associated proteins across cancer lineages are UBE4A, FAM76B_S193, and MRE11. Each is linked with RNF214 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNF214-to-partner and partner-to-RNF214 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF214 versus UBE4A in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF214→partner) and Y-score (partner→RNF214) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBE4A →	+0.252	+0.543	<.001	<.001	3	6
PDAC	FAM76B_S193 →	+0.488	+0.289	.001	<.001	3	6
BRCA	MRE11 →	+0.243	+0.360	.001	<.001	3	6
GBM	KMT2A →	+0.279	+0.319	<.001	<.001	3	5
GBM	NUMA1 →	+0.416	+0.382	<.001	<.001	3	5
GBM	NXF1 →	+0.318	+0.270	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,126 associations by consensus.

RNF214 vs UBE4A — HNSC

Explore this scatter interactively →