RNF19B

Across TCGA patient cohorts, RNF19B protein abundance is significantly associated with the RNA expression of many other genes, with 3,154 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNF19B-associated genes across cancer lineages are CUTC, TYW3, and CWF19L1. Each is linked with RNF19B in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF19B-to-partner and partner-to-RNF19B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF19B versus CUTC in LSCC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF19B→partner) and Y-score (partner→RNF19B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CUTC →	-0.748	-0.612	<.001	.002	3	2
LSCC	TYW3 →	-0.402	-0.616	.001	.008	3	2
LSCC	CWF19L1 →	-0.288	-0.525	.004	.002	3	2
PDAC	PSMC6 →	-0.321	-0.614	<.001	<.001	3	1
PDAC	SRP54 →	-0.182	-0.579	.008	.006	3	1
PDAC	SEC23A →	-0.288	-0.546	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,154 associations by consensus.

RNF19B vs CUTC — LSCC

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