RNF19B

Across TCGA patient cohorts, RNF19B mutation is significantly associated with the RNA expression of many other genes, with 766 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF19B-associated genes across cancer lineages are MIR6806, MIR527, and RNU6-276P. Each is linked with RNF19B in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF19B-to-partner and partner-to-RNF19B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6806 grouped by RNF19B-low versus RNF19B-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF19B→partner) and Y-score (partner→RNF19B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MIR6806 →	+0.686	+3.634	<.001	.004	3	2
LGG	MIR527 →	+0.348	+7.977	<.001	.007	3	1
LGG	RNU6-276P →	+0.318	+7.977	<.001	.007	3	1
LGG	IGHVII-67-1 →	+0.552	+7.977	<.001	.007	3	1
UCEC	LINC01607 →	-0.715	-3.563	<.001	.002	3	1
UCEC	CWC25 →	+0.471	+2.447	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 766 associations by consensus.

MIR6806 by RNF19B expression — STAD

Explore this box plot interactively →