RNF167

Across TCGA patient cohorts, RNF167 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF167-associated genes across cancer lineages are eIF4E, INPP4B, and Ku80. Each is linked with RNF167 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF167-to-partner and partner-to-RNF167 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by RNF167-low versus RNF167-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF167→partner) and Y-score (partner→RNF167) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.216	+2.820	.041	.035	3	1
UCEC	INPP4B →	-0.361	-2.999	.026	.035	3	1
UCEC	Ku80 →	+0.233	+2.335	.049	.020	3	1
UCEC	MEK1 →	+0.561	+3.169	.002	.019	3	1
UCEC	Notch1 →	+0.181	+2.321	.010	.035	3	1
UCEC	PCNA →	+0.253	+3.169	.020	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

eIF4E by RNF167 expression — UCEC

Explore this box plot interactively →