RNF167

Across TCGA pan-cancer cohorts, RNF167 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated RNF167 data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RNF167 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNF167 expression acts as an unfavorable survival marker, although some lineages such as PAAD and KIRC show a favorable association.

PAAD, KICH, and ACC are the cancer types where RNF167 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.551	0.240	<.001	81	view →
KICH	DFS	Median	III,IV	0.240	1.000	.001	64	view →
ACC	DFS	Tertile	All	0.206	0.730	<.001	51	view →
KIRC	DFS	Median	All	0.713	0.540	<.001	45	view →
LUAD	DFS	Tertile	II,III,IV	0.259	0.574	<.001	40	view →
LGG	OS	Tertile	All	0.402	0.573	<.001	36	view →
COAD	DFS	Quartile	IV	0.284	0.612	.006	28	view →
SCLC	OS	Median	All	0.761	0.518	.001	27	view →
UVM	DFS	Quartile	All	0.422	0.812	.006	26	view →
ESCA	DFS	Median	All	1.000	0.427	.001	21	view →
CHOL	DFS	Quartile	All	0.087	0.617	.019	19	view →
KIRP	DFS	Tertile	IV	0.370	0.654	.021	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

RNF167–PAAD (OS)

Open the PAAD breakdown →