RNF167

Across TCGA pan-cancer cohorts, RNF167 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RNF167’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNF167 RNA is repressed in tumor relative to normal tissue. In most cancer types RNF167 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and KIRP are the cancer types where RNF167 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNF167 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.168	<.001	9	view →
THCA	Male	III,IV	−0.564	<.001	9	view →
KIRP	All	II,III,IV	+0.675	<.001	7	view →
LIHC	All	II,III,IV	+0.406	<.001	7	view →
BRCA	All	III,IV	+0.293	.008	6	view →
HNSC	All	All	+0.271	.004	6	view →
CHOL	Male	All	+1.233	<.001	5	view →
READ	All	II,III,IV	−0.609	<.001	5	view →
LUAD	All	All	−0.295	<.001	5	view →
COAD	All	All	−0.267	.008	4	view →
KIRC	All	All	+0.259	<.001	3	view →
PRAD	All	All	−0.145	.029	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RNF167–KICH

Open the KICH breakdown →