RNF145

Across TCGA patient cohorts, RNF145 protein abundance is significantly associated with the RNA expression of many other genes, with 1,837 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RNF145-associated genes across cancer lineages are CSNK1A1, DIAPH1, and NECTIN4. Each is linked with RNF145 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF145-to-partner and partner-to-RNF145 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF145 versus CSNK1A1 in LSCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF145→partner) and Y-score (partner→RNF145) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CSNK1A1 →	+0.480	+0.514	<.001	<.001	3	2
LUAD	DIAPH1 →	+0.426	+0.357	.002	.003	3	2
LUAD	NECTIN4 →	+0.855	+0.446	.001	<.001	3	2
LSCC	BAG3 →	+0.804	+0.524	<.001	<.001	3	2
LSCC	NACC1 →	+0.466	+0.361	<.001	.001	3	2
LUAD	SQSTM1 →	+0.618	+0.353	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,837 associations by consensus.

RNF145 vs CSNK1A1 — LSCC

Explore this scatter interactively →