RNF144B

Across TCGA patient cohorts, RNF144B mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF144B-associated genes across cancer lineages are ACC_pS79, Ku80, and Tuberin. Each is linked with RNF144B in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF144B-to-partner and partner-to-RNF144B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC_pS79 grouped by RNF144B-low versus RNF144B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF144B→partner) and Y-score (partner→RNF144B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC_pS79 →	+0.502	+2.817	.002	.036	3	1
UCEC	Ku80 →	+0.295	+3.179	.009	.010	3	1
UCEC	Tuberin →	+0.433	+3.584	<.001	.002	3	1
UCEC	VHL →	-0.934	-3.169	.004	.019	3	1
UCEC	Cyclin-B1 →	+0.544	+2.459	.045	.020	3	1
UCEC	cIAP →	+0.152	+3.009	.021	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ACC_pS79 by RNF144B expression — UCEC

Explore this box plot interactively →