RNF144B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RNF144B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF144B-associated genes across cancer lineages are OR10W1, SIGLECL1, and ODF4. Each is linked with RNF144B in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF144B-to-partner and partner-to-RNF144B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by RNF144B-low versus RNF144B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF144B→partner) and Y-score (partner→RNF144B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR10W1 →+0.022+4.977<.001.00731
LARGE_INTESTINESIGLECL1 →+0.022+4.977<.001.00731
BLOOD_LeukemiaODF4 →+0.043+4.922<.001.00931
BLOOD_LeukemiaSLC22A12 →+0.006+5.539<.001.00331
BLOOD_LeukemiaFAM240A →+0.025+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR10W1 by RNF144B expression — LARGE_INTESTINE

Box plot of OR10W1 in RNF144B-low vs RNF144B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration