RNF125

Across TCGA patient cohorts, RNF125 mutation is significantly associated with the RNA expression of many other genes, with 974 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF125-associated genes across cancer lineages are RNA5SP387, MIR670, and RNU6ATAC17P. Each is linked with RNF125 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF125-to-partner and partner-to-RNF125 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP387 grouped by RNF125-low versus RNF125-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF125→partner) and Y-score (partner→RNF125) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP387 →	+0.628	+5.177	<.001	.007	3	2
LUSC	MIR670 →	+0.413	+4.578	<.001	.005	3	2
COAD	RNU6ATAC17P →	+0.628	+4.209	.003	.009	3	2
UCEC	RN7SKP286 →	+0.043	+4.153	<.001	.005	3	2
UCEC	BNIP3P41 →	+0.014	+4.571	<.001	.002	3	2
UCEC	MYO19 →	+0.500	+3.724	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 974 associations by consensus.

RNA5SP387 by RNF125 expression — BLCA

Explore this box plot interactively →