RNF125

Across TCGA cell cohorts, RNF125 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,723 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RNF125-associated GO terms across cancer lineages are Blood vessel morphogenesis, Acrosomal vesicle exocytosis, and Neural crest cell differentiation. Each is linked with RNF125 in more than 9 cancer types. Because this analysis shows association rather than direction, both RNF125-to-partner and partner-to-RNF125 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood vessel morphogenesis grouped by RNF125-low versus RNF125-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF125→partner) and Y-score (partner→RNF125) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Blood vessel morphogenesis →	-0.057	-1.056	<.001	<.001	3	9
BREAST	Acrosomal vesicle exocytosis →	+0.699	+0.396	.004	.006	2	10
BLOOD_Lymphoma	Neural crest cell differentiation →	-0.042	-1.244	.007	<.001	3	8
BLOOD_Lymphoma	Pigment biosynthetic process →	+0.070	+1.247	.001	.002	3	8
LUNG_NSCLC_LUSC	Complement-mediated synapse pruning →	-1.965	-0.822	<.001	<.001	3	7
OESOPHAGUS	Cell-substrate adhesion →	-0.135	-1.126	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,723 associations by consensus.

Blood vessel morphogenesis by RNF125 expression — OESOPHAGUS

Explore this box plot interactively →