RNF125

Across TCGA cell cohorts, RNF125 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF125-associated genes across cancer lineages are TAFA1 and ARMS2. Each is linked with RNF125 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF125-to-partner and partner-to-RNF125 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAFA1 grouped by RNF125-low versus RNF125-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF125→partner) and Y-score (partner→RNF125) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAFA1 →	+0.329	+4.688	<.001	<.001	3	1
LARGE_INTESTINE	ARMS2 →	+0.244	+3.938	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TAFA1 by RNF125 expression — LARGE_INTESTINE

Explore this box plot interactively →