RNF113B

Across TCGA patient cohorts, RNF113B mutation is significantly associated with the RNA expression of many other genes, with 2,046 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF113B-associated genes across cancer lineages are UBE2L2, SLC25A5P9, and MIR4774. Each is linked with RNF113B in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF113B-to-partner and partner-to-RNF113B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2L2 grouped by RNF113B-low versus RNF113B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF113B→partner) and Y-score (partner→RNF113B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	UBE2L2 →	+0.344	+2.992	.001	.006	3	2
READ	SLC25A5P9 →	+0.175	+4.724	<.001	.003	3	2
READ	MIR4774 →	+0.627	+5.257	<.001	.002	3	2
READ	MIR4797 →	+0.819	+5.054	<.001	.001	3	2
SKCM	RNA5SP444 →	+0.282	+5.469	<.001	.002	3	2
UCEC	ZNHIT3 →	+0.415	+2.981	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,046 associations by consensus.

UBE2L2 by RNF113B expression — COAD

Explore this box plot interactively →